PA26 Recombinant Antibody, AbBy Fluor-750 Conjugated, BF750, Rabbit

Produktübersicht

• Artikelname: PA26 Recombinant Antibody, AbBy Fluor-750 Conjugated, BF750, Rabbit
• Artikelnummer: BSS-BSM-62280R-BF750
• Hersteller Artikelnummer: bsm-62280R-BF750
• Alternativnummer: BSS-BSM-62280R-BF750-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: BF750
• Alternative Synonym: PA26, sesn1, SEST1, sestrin 1.

Produktbeschreibung

Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 27244
• UniProt: Q9Y6P5
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human Sestrin 1
• Target-Kategorie: PA26

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), FCM(1ug/Test)