SMG1 Recombinant Antibody, Cy5.5 Conjugated, Rabbit

Produktübersicht

• Artikelname: SMG1 Recombinant Antibody, Cy5.5 Conjugated, Rabbit
• Artikelnummer: BSS-BSM-62379R-CY5.5
• Hersteller Artikelnummer: bsm-62379R-Cy5.5
• Alternativnummer: BSS-BSM-62379R-CY5.5-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Cy5.5
• Alternative Synonym: 61E3.4, ATX, hSMG1, LIP, smg1.

Produktbeschreibung

Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]-Q. Plays a central role in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating UPF1/RENT1. Recruited by release factors to stalled ribosomes together with SMG8 and SMG9 (forming the SMG1C protein kinase complex), and UPF1 to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 23049
• UniProt: Q96Q15
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human SMG1
• Target-Kategorie: SMG1

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000)