ERCC8 Recombinant Antibody, APC-Cy7 Conjugated, APC/Cy7, Rabbit

Produktübersicht

• Artikelname: ERCC8 Recombinant Antibody, APC-Cy7 Conjugated, APC/Cy7, Rabbit
• Artikelnummer: BSS-BSM-62393R-APC-CY7
• Hersteller Artikelnummer: bsm-62393R-APC-Cy7
• Alternativnummer: BSS-BSM-62393R-APC-CY7-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Konjugation: APC/Cy7
• Alternative Synonym: CKN1, CSA, ERCC8.

Produktbeschreibung

Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner, ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 1161
• UniProt: Q13216
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human ERCC8
• Target-Kategorie: ERCC8

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000)