RGMA Recombinant Antibody, Cy5 Conjugated, Rabbit

Produktübersicht

• Artikelname: RGMA Recombinant Antibody, Cy5 Conjugated, Rabbit
• Artikelnummer: BSS-BSM-62481R-CY5
• Hersteller Artikelnummer: bsm-62481R-Cy5
• Alternativnummer: BSS-BSM-62481R-CY5-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Cy5
• Alternative Synonym: Repulsive guidance molecule A, RGM, RGM domain family member A, RGMA.

Produktbeschreibung

Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 56963
• UniProt: Q96B86
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human Repulsive guidance molecule A
• Target-Kategorie: RGMA

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000)