BLNK Recombinant Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: BLNK Recombinant Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BSM-62608R-BIOTIN
• Hersteller Artikelnummer: bsm-62608R-Biotin
• Alternativnummer: BSS-BSM-62608R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Biotin
• Alternative Synonym: AGM4, BASH, Bca, BLNK, Ly57, Lyw57, SLP65.

Produktbeschreibung

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 29760
• UniProt: Q8WV28
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human BLNK
• Reinheit: Purified by Protein A.
• Target-Kategorie: BLNK

Anwendungsbeschreibung

• Application Verdünnung: WB(WB=1:500-2000), IHC-P(IHC-P=1:50-200), IHC-F(IHC-F=1:50-200)