p45 NF-E2 Recombinant Antibody, PE Conjugated, Rabbit
Artikelnummer:
BSS-BSM-62800R-PE
Hersteller Artikelnummer:
bsm-62800R-PE
Alternativnummer:
BSS-BSM-62800R-PE-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, WB
Spezies Reaktivität:
Human
Konjugation:
PE
Alternative Synonym:
nfe2 , Nuclear factor, p45 NFE2.
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.