SARS-CoV-2 S-Protein ACE2 Binding Domain Antibody, IgG1, Clone: [5G8], Unconjugated, Mouse, Monoclonal

Produktübersicht

• Artikelname: SARS-CoV-2 S-Protein ACE2 Binding Domain Antibody, IgG1, Clone: [5G8], Unconjugated, Mouse, Monoclonal
• Artikelnummer: BSS-BSM-70256M
• Hersteller Artikelnummer: bsm-70256M
• Alternativnummer: BSS-BSM-70256M-100
• Hersteller: Bioss
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Virus
• Konjugation: Unconjugated
• Alternative Synonym: sars-cov-2

Produktbeschreibung

The novel SARS-coronavirus 2 (SARS-CoV-2) which causes the disease COVID-19 has been shown to utilize the SARS-CoV receptor ACE2 for entry into human cells (Hoffman, M. et al., Cell 2020). The entry of a coronavirus into host cells is mediated by the viral surface-anchored transmembrane spike (S) glycoprotein which is composed of two functional subunits, S1 which binds the receptor and S2 which fuses the membrane (Walls, AC et.al., Cell 2020). S1 contains a receptor-binding domain (RBD) which specifically recognizes ACE2 as its receptor (Wan, Y. et al., 2020).

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: Lot Dependent
• Klon-Bezeichnung: [5G8]
• Isotyp: IgG1
• UniProt: P0DTC2
• Puffer: PBS + 50% glycerol and 5 mm NaN3
• Quelle: Recombinant SARS-CoV-2 S-Protein construct containing the ACE2 binding domain expressed in and purified from E. coli.
• Target-Kategorie: SARS-CoV-2 S-Protein ACE2 Binding Domain

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000)