CAB27, CALB 1, CALB, CALB1, Calbindin 1 28kDa, Calbindin-D-28K, Calbindin D28, D 28K, D28K, Vitamin D dependent calcium binding protein, Vitamin D dependent calcium binding protein avian type, Vitamin D dependent calcium binding protein avian-type, Vitamin D-dependent calcium-binding protein, CALB1_RAT.
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
Proben:
FFPE tissue
Target-Kategorie:
Calbindin
IHC0106R
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