Human NFKB p65 Ready-To-Use IHC Kit

Produktübersicht

• Artikelname: Human NFKB p65 Ready-To-Use IHC Kit
• Artikelnummer: BSS-IHC0206H
• Hersteller Artikelnummer: IHC0206H
• Alternativnummer: BSS-IHC0206H-50
• Hersteller: Bioss
• Kategorie: Kits/Assays
• Spezies Reaktivität: Human
• Alternative Synonym: p65, NF kB P65, NF-kB p65, NF-kB-p65, NFKBp65, NF-kappaBp65, NF-kBp65, Avian reticuloendotheliosis viral (v rel) oncogene homolog A, MGC131774, NFKB 3, NFKB3, RELA.

Produktbeschreibung

Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.

Produkteigenschaften

• Proben: FFPE tissue
• Target-Kategorie: Human NFKB

Bilder

IHC0206H