Human CD38 Ready-To-Use IHC Kit

Produktübersicht

• Artikelname: Human CD38 Ready-To-Use IHC Kit
• Artikelnummer: BSS-IHC0228H
• Hersteller Artikelnummer: IHC0228H
• Alternativnummer: BSS-IHC0228H-50
• Hersteller: Bioss
• Kategorie: Kits/Assays
• Spezies Reaktivität: Human
• Alternative Synonym: Cd38, Cd38-rs1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 2-phospho-ADP-ribosyl cyclase, 2-phospho-ADP-ribosyl cyclase/2-phospho-cyclic-ADP-ribose transferase, 2-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, ADPRC 1, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10, CD38_HUMAN.

Produktbeschreibung

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richters Syndrome.

Produkteigenschaften

• Proben: FFPE tissue
• Target-Kategorie: Human CD38

Bilder

IHC0228H