AP-1, c-Jun, Rjg-9, Activator protein 1, AP 1, AP1, c Jun, JUN, jun oncogene, P39, Proto oncogene c Jun, Transcription factor AP 1.
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5-TGA[CG]TCA-3. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells
Proben:
FFPE tissue
Target-Kategorie:
Mouse Phospho-c-Jun (Thr91+Thr93)
IHC0357M
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