AF, AF-1, Af1, angiocidin, ASF, MCB1, PSMD4, pUB-R5, Rpn10, S5Aa
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.
Proben:
FFPE tissue
Target-Kategorie:
Human PSMD4
IHC0449H
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