Human eIF4E Ready-To-Use IHC Kit

Produktübersicht

• Artikelname: Human eIF4E Ready-To-Use IHC Kit
• Artikelnummer: BSS-IHC0533H
• Hersteller Artikelnummer: IHC0533H
• Alternativnummer: BSS-IHC0533H-50
• Hersteller: Bioss
• Kategorie: Kits/Assays
• Spezies Reaktivität: Human
• Alternative Synonym: AUTS19, CBP, EG668879, eIF-4E, EIF4E, Eif4e-ps, EIF4E1, EIF4EL1, EIF4F, If4e, eIF-4E, eukaryotic translation initiation factor 4E, Messanger RNA Cap Binding Protein eIF 4E, IF4E_HUMANa

Produktbeschreibung

eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.

Produkteigenschaften

• Proben: FFPE tissue
• Target-Kategorie: Human eIF4E

Bilder

IHC0533H