Human GH1 Ready-To-Use IHC Kit

Produktübersicht

• Artikelname: Human GH1 Ready-To-Use IHC Kit
• Artikelnummer: BSS-IHC0546H
• Hersteller Artikelnummer: IHC0546H
• Alternativnummer: BSS-IHC0546H-50
• Hersteller: Bioss
• Kategorie: Kits/Assays
• Spezies Reaktivität: Human
• Alternative Synonym: GHB5, GH 1, GH, GH N, GH-N, GH1, GHN, Growth Hormone 1, Growth hormone 1 variant 1, Growth hormone 1 variant 2, Growth hormone, Growth Hormone Normal, Growth Hormone Pituitary, Growth hormone, normal, Growth hormone, pituitary, HG1,hGH N, hGH-N, HGHN, IGHD1B, Pituitary Growth Hormone, RNGHGP, SOMA_HUMAN, Somatotropin C, Somatotropin, Somatotropin I Precursora

Produktbeschreibung

Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.

Produkteigenschaften

• Proben: FFPE tissue
• Target-Kategorie: Human GH1

Bilder

IHC0546H