Human ULK3 Ready-To-Use IHC Kit

Produktübersicht

• Artikelname: Human ULK3 Ready-To-Use IHC Kit
• Artikelnummer: BSS-IHC0562H
• Hersteller Artikelnummer: IHC0562H
• Alternativnummer: BSS-IHC0562H-50
• Hersteller: Bioss
• Kategorie: Kits/Assays
• Spezies Reaktivität: Human
• Alternative Synonym: 1200015E14Rik, ULK3, DKFZP434C131, FLJ90566, Serine/threonine-protein kinase ULK3, ULK3_HUMAN, unc 51 like kinase 3 (C. elegans), Unc-51-like kinase 3a

Produktbeschreibung

ULK3 or unc-51-like kinase 3 is a member of the serine/threonine kinase family that is involved in the SHH signaling pathway as a positive regulator of GLI proteins. ULK3 enhances endogenous and over-expressed GLI transcriptional activity in cultured cells and alters its subcellular localization. Furthermore, ULK3 phosphorylates GLI proteins in vitro. ULK3 is widely expressed and its expression is higher in a number of tissues where SHH signaling is known to be active, again suggesting that ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins.

Produkteigenschaften

• Proben: FFPE tissue
• Target-Kategorie: Human ULK3

Bilder

IHC0562H