Human CD15/SSEA1 Ready-To-Use IHC Kit

Produktübersicht

• Artikelname: Human CD15/SSEA1 Ready-To-Use IHC Kit
• Artikelnummer: BSS-IHC0586H
• Hersteller Artikelnummer: IHC0586H
• Alternativnummer: BSS-IHC0586H-50
• Hersteller: Bioss
• Kategorie: Kits/Assays
• Spezies Reaktivität: Human
• Alternative Synonym: LeX, CD15, ELFT, FCT3A, FUTIV, SSEA-1, FUC-TIV, FCT3A, Fucosyltransferase 4, Fucosyltransferase IV, FUT4, SSEA 1a

Produktbeschreibung

CD15 (Lewis X, Le(x), stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkins disease.

Produkteigenschaften

• Proben: FFPE tissue
• Target-Kategorie: Human CD15/SSEA1

Bilder

IHC0586H