Ap-2 (a), AP-2alpha, Ap2, AP2alpha, Tcfap2a, TFAP2, Activating enhancer binding protein 2 alpha, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP 2 transcription factor, AP 2alpha, AP-2, AP-2 transcription factor, AP2, AP2 Transcription Factor, AP2-alpha, AP2A_HUMAN, AP2TF, BOFS, FLJ51761, TFAP 2, TFAP 2A, TFAP2, TFAP2A, Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha), Transcription factor AP-2-alpha, Transcription factor AP2 alphaa
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5-GCCNNNGGC-3 and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
Proben:
FFPE tissue
Target-Kategorie:
Human AP2 alpha
IHC0637H
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