Human CD50 Ready-To-Use IHC Kit

Produktübersicht

• Artikelname: Human CD50 Ready-To-Use IHC Kit
• Artikelnummer: BSS-IHC0667H
• Hersteller Artikelnummer: IHC0667H
• Alternativnummer: BSS-IHC0667H-50
• Hersteller: Bioss
• Kategorie: Kits/Assays
• Spezies Reaktivität: Human
• Alternative Synonym: intercellular adhesion molecules-3, Intercellular adhesion molecule 3, ICAM-3, ICAM 3, CD50, CDW 50, CDW50, ICAM 3, ICAM R, ICAMR, CD 50, CD50 antigen, ICAM-R, ICAM3, ICAM3_HUMANa

Produktbeschreibung

CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages, this process is involved in dialogue between dendritic cells and granulocytes.

Produkteigenschaften

• Proben: FFPE tissue
• Target-Kategorie: Human CD50

Bilder

IHC0667H