Mouse DARPP32 Ready-To-Use IHC Kit

Produktübersicht

• Artikelname: Mouse DARPP32 Ready-To-Use IHC Kit
• Artikelnummer: BSS-IHC0670M
• Hersteller Artikelnummer: IHC0670M
• Alternativnummer: BSS-IHC0670M-50
• Hersteller: Bioss
• Kategorie: Kits/Assays
• Spezies Reaktivität: Mouse
• Alternative Synonym: AU040756, DARPP-32, DARPP32, DARPP32 (phospho T75), p-DARPP32 (phospho T75), PPP1R1B(phospho T75), DARPP 32, Dopamine and cAMP regulated neuronal phosphoprotein, Dopamine and cAMP regulated phosphoprotein DARPP 32, Dopamine and cAMP regulated phosphoprotein DARPP32, FLJ20940, IPPD, Neuronal phosphoprotein DARPP 32, PPP1R1B, Protein phosphatase 1 regulatory (inhibitor) subunit 1B, Protein phosphatase 1 regulatory subunit 1B, PPR1B_HUMANa

Produktbeschreibung

DARPP-32 is a dopamine (DA) and AMP-regugated ~32 kDa phosphoprotein that is associated with dopaminoceptive neurons. The protein inhibits Protein Phosphatase I when it is phosphorylated on Thr34. In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA. Phosphorylation of DARPP-32 is thought to play a critical role in the regugation of dopaminergic neurotransmission. In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac.

Produkteigenschaften

• Proben: FFPE tissue
• Target-Kategorie: Mouse DARPP32

Bilder

IHC0670M