Caspase-3 (Phospho-S150) polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: Caspase-3 (Phospho-S150) polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-AP0249
• Hersteller Artikelnummer: AP0249
• Alternativnummer: BWT-AP0249-50UL,BWT-AP0249-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic phosphopeptide derived from human Caspase-3 around the phosphorylation site of Serine 150.
• Konjugation: Unconjugated
• Alternative Synonym: Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, Caspase-3 subunit p17, Caspase-3 subunit p12, CASP3, CPP32

Produktbeschreibung

Caspase-3 (CPP-32, Apopain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires the aspartic acid residue at the P1 position.

Produkteigenschaften

• Molekulargewicht: ~ 33 kDa
• UniProt: P42574
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:1000~1:2000
• Anwendungsbeschreibung: Caspase-3 (Phospho-S150) polyclonal antibody detects endogenous levels of Caspase-3 protein only when phosphorylated at Ser150.