AURKB/C (K197) polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-AP0464
Artikelname: AURKB/C (K197) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-AP0464
Hersteller Artikelnummer: AP0464
Alternativnummer: BWT-AP0464-50UL,BWT-AP0464-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 163-213 of Human AURKB.
Konjugation: Unconjugated
Alternative Synonym: Aurora kinase B, Aurora 1, Aurora- and IPL1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, ARK-2, Aurora-related kinase 2, STK-1, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 5,Serine/threonine-protein kinase aurora-B, AURKB, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5, Aurora kinase C, Aurora 3, Aurora/IPL1-related kinase 3, ARK-3, Aurora-related kinase 3, Aurora/IPL1/Eg2 protein 2, Serine/threonine-protein kinase 13, Serine/threonine-protein kinase aurora-C, AURKC, AIE2, AIK3, AIRK3, ARK3, STK13
Aurora kinases belong to a highly conserved family of mitotic serine/threonine kinases with three members identified among mammals: Aurora A, B, and C. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
Molekulargewicht: ~ 55, 40, 45 kDa
UniProt: Q96GD4
Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 108% (by SDS-PAGE).
Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung: WB:1:500~1:1000
Anwendungsbeschreibung: AURKB/C (K197) polyclonal antibody detects endogenous levels of AURKB and AURKC protein.