Synthetic phosphopeptide derived from human PPARgamma around the phosphorylation site of Serine 112.
Konjugation:
Unconjugated
Alternative Synonym:
Peroxisome proliferator-activated receptor gamma, Short name=PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, PPARG, NR1C3, PPAR gamma, PPARgamma
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a member of the ligand-activated nuclear receptor superfamily and functions as a transcriptional activator. PPARgamma is preferentially expressed in adipocytes as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipid metabolism, PPARgamma also modulates insulin sensitivity, cell proliferation and inflammation. PPARgamma transcriptional activity is inhibited by MAP kinase phosphorylation of PPARgamma at Ser84.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Application Verdünnung:
WB: 1:500~1:1000 IP: 1:50~1:200
Anwendungsbeschreibung:
PPARgamma(Phospho-Ser112) polyclonal antibody detects endogenous levels of PPARgamma protein only when phosphorylated at Ser112.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
