IFN-gamma Receptor II, also known as IFNGR2 and IFNGT1, is a transmembrane protein belonging to the type II cytokine receptor family. IFNGR2 is a non-ligand-binding beta chain of the IFN-gamma receptor. It is an integral part of the IFN-gamma signaling transduction pathway and is likely to interact with GAF, JAK1 and JAK2. Defects in IFNGR2 are a cause of autosomal recessive Mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.
Molekulargewicht:
38-40 kDa, observed by reducing SDS-PAGE.
Quelle:
CHO
Reinheit:
> 95% as analyzed by SDS-PAGE.
Formulierung:
Sterile Filtered White lyophilized (freeze-dried) powder.
