Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages[1]. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells [2]. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers [1][3][4].
Molekulargewicht:
32-40 kDa, observed by non-reducing SDS-PAGE.
Quelle:
CHO
Reinheit:
> 95% as analyzed by SDS-PAGE.
Formulierung:
Sterile Filtered White lyophilized (freeze-dried) powder.
