Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors, fms-like tyrosine kinase (flt-1), KDR gene product (the mouse homolog of KDR is the flk-1 gene product) and the flt4 gene product.
Molekulargewicht:
20~26 kDa, observed by reducing SDS-PAGE.
Quelle:
HEK 293
Reinheit:
> 95% as analyzed by SDS-PAGE.
Formulierung:
Sterile Filtered White lyophilized (freeze-dried) powder.
