Galectin-3 (N174) polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: Galectin-3 (N174) polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS1137
• Hersteller Artikelnummer: BS1137
• Alternativnummer: BWT-BS1137-50UL,BWT-BS1137-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 140-190 of Human Galectin-3.
• Konjugation: Unconjugated
• Alternative Synonym: CBP35, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3, MAC2, Galectin 3, Galectin3

Produktbeschreibung

The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. galectin-3 mediates the endocytosis of beta-1 Integrins in a lactose-dependant manner and is associated with thyroid malignancy and Crohns disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.

Produkteigenschaften

• Molekulargewicht: ~ 30 kDa
• UniProt: P17931
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
• Anwendungsbeschreibung: Galectin-3 (N174) polyclonal antibody detects endogenous levels of Galectin-3 protein.