SAE2 (S621) polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: SAE2 (S621) polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS1485
• Hersteller Artikelnummer: BS1485
• Alternativnummer: BWT-BS1485-50UL,BWT-BS1485-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 598-640 of Human SAE2.
• Konjugation: Unconjugated
• Alternative Synonym: SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, UBA2, SAE2, UBLE1B, HRIHFB2115

Produktbeschreibung

The human UBiquitin Activating domain 2 (UBA2) gene is located on chromosome 19q12. Human UBA2 could form a beta mercaptoethanol-sensitive conjugate with members of the sentrin family, but not with ubiquitin of NEDD8 in the presence of AOS1. The recombinant proteins, Sua1p and hUba2, form a complex. In this complex, hUba2 binds SUMO-1, which gives the complex the activity of the SUMO-1 activating enzyme. Therefore, UBA2 has been found to be a component of the sentrin-activating enzyme complex.

Produkteigenschaften

• Molekulargewicht: ~ 90 kDa
• UniProt: Q9UBT2
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
• Anwendungsbeschreibung: Uba2 (S621) polyclonal antibody detects endogenous levels of Uba2 protein.