Synthetic peptide, corresponding to amino acids 543-590 of Human B-Myb.
Konjugation:
Unconjugated
Alternative Synonym:
Myb-related protein B, B Myb, Myb-like protein 2, MYBL2, BMYB
c-Myb is the cellular homolog of the leukemogenic avian retroviral protein v-Myc. c-Myb is expressed predominantly in immature and rapidly dividing hematopoietic cells, and cellular levels of c-Myb substantially decreases as cells reach terminal differentiation. B-Myb is expressed in a wide variety of proliferating cells, with levels accumulating during the G1 to S phase transition. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB: 1:500~1:1000 IF: 1:50~1:200
Anwendungsbeschreibung:
B-Myb (G573/577) polyclonal antibody detects endogenous levels of B-Myb protein.
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