VEGI (F141) polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-BS1899
Artikelname: VEGI (F141) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-BS1899
Hersteller Artikelnummer: BS1899
Alternativnummer: BWT-BS1899-50UL,BWT-BS1899-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IF, IHC
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 111-160 of Human VEGI.
Konjugation: Unconjugated
Alternative Synonym: Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1, Vascular endothelial cell growth inhibitor, TNFSF15, TL1, VEGI
Vascular endothelial cell growth inhibitor (VEGI also known as TNFRSF15 or TL1), a member of the TNF superfamily, has a signaling pathway similar to TNF and is most likely a multifunctional cytokine. VEGI is found in brain, reproductive, and late developmental stage embryonic tissues and expressed predominantly in endothelial cells. VEGI is an angiogenesis inhibitor of the TNF family and functions in part by directly inhibiting endothelial cell proliferation.VEGI may act as an autocrine factor to induce apoptosis in endothelial cells via activation of multiple signaling pathways, including stress protein kinases as well as certain caspases
Molekulargewicht: ~ 25 kDa
UniProt: O95150
Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung: IHC: 1:50~1:200 IF: 1:50~1:200
Anwendungsbeschreibung: VEGI (F141) polyclonal antibody detects endogenous levels of VEGI protein.