PFKL (E724) polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: PFKL (E724) polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS1943
• Hersteller Artikelnummer: BS1943
• Alternativnummer: BWT-BS1943-50UL,BWT-BS1943-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 700-750 of Human PFKL.
• Konjugation: Unconjugated
• Alternative Synonym: 6-phosphofructokinase, liver type, Phosphofructokinase 1, Phosphohexokinase, Phosphofructo-1-kinase isozyme B, PFK-B,

Produktbeschreibung

Phosphofructokinase (PFK) catalyzes the phosphorylation of fructose-6-phosphate in glycolysis. There are three isozymes: muscle-type, liver-type, and platelet-type. The liver-type PFK (PFKL) is the predominant subunit of PFK found in the liver. Research studies have shown that because of its location on chromosome 21, this enzyme is overexpressed in Down Syndrome/trisomy 21. PFKL also may have a role in the physiological response to a low fat diet.

Produkteigenschaften

• Molekulargewicht: ~ 85 kDa
• UniProt: P17858
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: IHC: 1:50~1:200
• Anwendungsbeschreibung: PFKL (E724) polyclonal antibody detects endogenous levels of PFKL protein.