TRAIL (S63) polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-BS2007
Artikelname: TRAIL (S63) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-BS2007
Hersteller Artikelnummer: BS2007
Alternativnummer: BWT-BS2007-50UL,BWT-BS2007-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IF, IHC
Spezies Reaktivität: Human
Immunogen: Synthetic peptide, corresponding to amino acids 50-100 of Human TRAIL.
Konjugation: Unconjugated
Alternative Synonym: TNF-related apoptosis-inducing ligand, Protein TRAIL, Apo-2 ligand, Apo-2L, CD253 antigen, TRAIL, 8743, TNFSF10, 603598, P50591, APO2L, Apo-2L, TL2, TRAIL,
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also referred to as Apo2 ligand, first identified based on its sequence homology to TNF and Fas/Apo ligand is a member of the TNF family of cytokines and either exists as a type II membrane or soluble protein. TRAIL induces apoptosis in a variety of transformed cell lines and plays a role in anti-tumor and anti-viral immune surveillance. TRAIL signals via binding with death receptors DR4 (TRAIL-R1) (4) and DR5 (TRAIL-R2) which can trigger apoptosis as well as NF-kappaB activation.
Molekulargewicht: ~34 kDa
UniProt: P50591
Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung: IHC: 1:50~1:200 IF: 1:50~1:200
Anwendungsbeschreibung: TRAIL (S63) polyclonal antibody detects endogenous levels of TRAIL protein.