The Eph subfamily represents the largest group of receptor protein kinases identified to date. There is increasing evidence that they are involved in central nervous system function and in development. Ligands for Eph receptors include ephrin-A1 (LERK-1/B61), identified as a ligand for the EphA2 (Eck) receptor, ephrin-A2 (ELF-1), identified as a ligand for the EphA3 and EphA4 (Sek) receptors, ephrin-A3 (LERK-3), identified as a ligand for EphA5 (Ehk1) and EphA3 (Hek) receptors, ephrin-A4 (LERK-4), identified as a ligand for the EphA3 receptor, ephrin-A5 (AL-1), identified as a ligand for EphA5 (REK7), ephrin-B1 (LERK-2), identified as a ligand for the EphB1 (Elk) and EphB2 (Cek5) receptors, ephrin-B2 (LERK-5), identified as a ligand for the EphB1, EphB3 (Cek10) and EphB2 receptors, and ephrin-B3 (LERK-8), identified as a ligand for EphB1.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Anwendungsbeschreibung:
Ephrin-A3 (E196) polyclonal antibody detects endogenous levels of Ephrin-A3 protein.
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