Caspase 4 (E124) polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: Caspase 4 (E124) polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS3686
• Hersteller Artikelnummer: BS3686
• Alternativnummer: BWT-BS3686-50UL,BWT-BS3686-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human Caspase 4.
• Konjugation: Unconjugated
• Alternative Synonym: Caspase-4, CASP-4, ICE(rel)-II, Protease ICH-2, Protease TX, Caspase-4 subunit 1, CASP4, ICH2, Caspase 4, Caspase4

Produktbeschreibung

A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks.

Produkteigenschaften

• Molekulargewicht: ~ 45 kDa
• UniProt: P49662
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: IHC: 1:50~1:200
• Anwendungsbeschreibung: Caspase-4 (E124) polyclonal antibody detects endogenous levels of Caspase-4 protein.