Synthetic peptide, corresponding to amino acids 280-330 of Human Rad51.
Konjugation:
Unconjugated
Alternative Synonym:
BRCC5, DNA repair protein RAD51 homolog 1, E coli RecA homolog, HGNC:9817, HRAD51, Homolog of E coli RecA, HsRad51, HsT16930, RAD51 S cerevisiae homolog, RAD51 homolog S. cerevisiae, RAD51A, RECA, Rad 51, RecA homolog E. coli, RecA like protein,
Rad51 is a recombinase that is essential for homologous recombination and double-strand break repair. It binds to single and double-stranded DNA, and has DNA-dependent ATPase activity. Rad51 unwinds duplex DNA and forms helical nucleoprotein filaments in a manner that is controlled through the action of DNA helicases that counteract nucleofilament formation. Rad51 interacts with BRCA1 and BRCA2, and also plays a role in p53-mediated signalling. Interaction of Rad51 with Chk1 kinase may occur in response to Chk1 phosphorylation
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB: 1:500~1:1000 IHC: 1:50~1:200
Anwendungsbeschreibung:
Rad51 (T309) polyclonal antibody detects endogenous levels of Rad51 protein.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
