A synthesized peptide derived from human Cyclin D1
Konjugation:
Unconjugated
Alternative Synonym:
CCND1,BCL1, D11S287E, PRAD1, U21B31, Cyclin D1,
Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.
