A synthesized peptide derived from human Phospho-Histone H3 (S10)
Konjugation:
Unconjugated
Alternative Synonym:
H3 histone, family 3A, H3 histone, family 3B (H3.3B), H3.3A, H3.3B, H33, H3F3, H3F3A, H3F3B, Histone H3.3,
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.
