BRE1-A, hBRE1, RING finger protein 20, E3 ubiquitin-protein ligase BRE1A, RNF20,
RNF20 is an E3 ubiquitin ligase protein that mediates monoubiquitination of histone H2B and the methylation of histone H3. It forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code