A synthesized peptide derived from human Phospho-PKR (T446)
Konjugation:
Unconjugated
Alternative Synonym:
E2AK2,E2AK2, EIF2AK1, EIF2AK2, MGC126524, PKR p68 kinase, PKR, PRKR,
PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.
