Cathepsin D Rabbit monoclonal antibody, Unconjugated
Artikelnummer:
BWT-BS40113
Hersteller Artikelnummer:
BS40113
Alternativnummer:
BWT-BS40113-50UL,BWT-BS40113-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FC, ICC, IHC, IP, WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
A synthesized peptide derived from human Cathepsin D
Konjugation:
Unconjugated
Alternative Synonym:
CATD, Cathepsin D, Cathepsin D heavy chain, Cathepsin D light chain, ceroid-lipofuscinosis, neuronal 10, CLN10, CPSD, CTSD, lysosomal aspartyl peptidase, lysosomal aspartyl protease, MGC2311
This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.
