TNF Receptor II Rabbit monoclonal antibody, Unconjugated

Produktübersicht

• Artikelname: TNF Receptor II Rabbit monoclonal antibody, Unconjugated
• Artikelnummer: BWT-BS40498
• Hersteller Artikelnummer: BS40498
• Alternativnummer: BWT-BS40498-50UL,BWT-BS40498-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, IHC, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human TNF Receptor II
• Konjugation: Unconjugated
• Alternative Synonym: CD120b, p75 TNF receptor, p80 TNF alpha receptor, Soluble TNFR1B variant 1, TBP-2, TBPII, TNF R75, TNFBR, TNFR-II, TNFR1B, TNFR2, TNFR80, TNFRII, Tnfrsf1b,

Produktbeschreibung

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Produkteigenschaften

• Molekulargewicht: 73kDa
• UniProt: P20333
• Reinheit: Affinity-chromatography
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
• Anwendungsbeschreibung: TNF Receptor II Antibody detects endogenous levels of total TNF Receptor II