Tau (phospho-S356) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer:
BWT-BS4195
Hersteller Artikelnummer:
BS4195
Alternativnummer:
BWT-BS4195-50UL,BWT-BS4195-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Synthetic phosphopeptide derived from human isoforms Tau-4 around the phosphorylation site of Serine 356.
Konjugation:
Unconjugated
Alternative Synonym:
Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU
Tau, also known as MAPT (microtubule-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to the cytoskeleton and the cell membrane, and contains four Tau/MAP repeats. Expressed in neuronal tissue and existing as multiple alternatively spliced isoforms, Tau functions to promote microtubule assembly and stability and is thought to be involved in the maintenance of neuronal polarity. Tau may also link microtubules with neural plasma membrane components and, addition to its role in microtubule stability, is also necessary for cytoskeletal plasticity.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB: 1:500~1:1000 IHC: 1:50~1:200
Anwendungsbeschreibung:
p-Tau (S356) polyclonal antibody detects endogenous levels of Tau only when phosphorylated at Ser673, isoforms Tau-4 phosphorylated at Ser356, and other isoforms phosphorylated at the corresponding Site.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
