Caspase-9 (phospho-T125) polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: Caspase-9 (phospho-T125) polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS4221
• Hersteller Artikelnummer: BS4221
• Alternativnummer: BWT-BS4221-50UL,BWT-BS4221-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthetic phosphopeptide derived from human Caspase-9 around the phosphorylation site of Threonine 125.
• Konjugation: Unconjugated
• Alternative Synonym: CASP 9, Caspase9, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6

Produktbeschreibung

Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6.

Produkteigenschaften

• Molekulargewicht: ~ 35,48 kDa
• UniProt: P55211
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: IHC: 1:50~1:200
• Anwendungsbeschreibung: p-Caspase-9 (T125) polyclonal antibody detects endogenous levels of Caspase-9 protein only when phosphorylated at Thr125.