FGFR1 (phospho-Y766) polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: FGFR1 (phospho-Y766) polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS4318
• Hersteller Artikelnummer: BS4318
• Alternativnummer: BWT-BS4318-50UL,BWT-BS4318-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthetic phosphopeptide derived from human FGFR1 around the phosphorylation site of Tyrosine 766.
• Konjugation: Unconjugated
• Alternative Synonym: Fibroblast growth factor receptor 1, FGFR-1, 2.7.10.1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD331, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, FGFR1

Produktbeschreibung

FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family containing an Ig-like domain and a tyrosine kinase domain. This receptor has multiple isoforms and is a Type I membrane protein. FGFR1 is a widely expressed membrane receptor, with distinct isoforms expressed in specific tissues. FGFR1 binds fibroblast growth factor and induces mitogenesis and cellular differentiation. Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis. FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform. FGFR1 has been shown to interact with N-cadherin and NCAM.

Produkteigenschaften

• Molekulargewicht: ~ 140 kDa
• UniProt: P11362
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: IHC: 1:50~1:200
• Anwendungsbeschreibung: p-FGFR1 (Y766) polyclonal antibody detects endogenous levels of FGFR1 only when phosphorylated at Tyr766.