Phospho-MLKL (Ser345) Recombinant Rabbit mAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-MLKL (Ser345) Recombinant Rabbit mAb, Unconjugated
• Artikelnummer: BWT-BS43185
• Hersteller Artikelnummer: BS43185
• Alternativnummer: BWT-BS43185-50UL,BWT-BS43185-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IP, WB
• Spezies Reaktivität: Mouse
• Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser345 of mouse MLKL
• Konjugation: Unconjugated
• Alternative Synonym: 9130019I15Rik

Produktbeschreibung

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain, however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Produkteigenschaften

• Molekulargewicht: 54 kDa
• UniProt: Q9D2Y4
• Reinheit: Affinity Purification
• Formulierung: Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:1000<br />IP: 1:100
• Anwendungsbeschreibung: IgG