A synthetic phosphopeptide corresponding to residues surrounding Ser432 of human p95 NBS1
Konjugation:
Unconjugated
Alternative Synonym:
ATV, NBS, P95, NBS1, AT-V1, AT-V2
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Application Verdünnung:
IHC: 1:100
Anwendungsbeschreibung:
IgG
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