A synthetic phosphopeptide corresponding to residues surrounding Thr680 of human BubR1
Konjugation:
Unconjugated
Alternative Synonym:
MVA1, SSK1, BUBR1, Bub1A, MAD3L, hBUBR1, BUB1beta
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
