Phospho-Crk p38 (Tyr221) Recombinant Rabbit mAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-Crk p38 (Tyr221) Recombinant Rabbit mAb, Unconjugated
• Artikelnummer: BWT-BS43341
• Hersteller Artikelnummer: BS43341
• Alternativnummer: BWT-BS43341-50UL,BWT-BS43341-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ICC, WB
• Spezies Reaktivität: Human
• Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Tyr221 of human Crk p38
• Konjugation: Unconjugated
• Alternative Synonym: p38, CRKII

Produktbeschreibung

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]

Produkteigenschaften

• Molekulargewicht: 38 kDa
• UniProt: P46108
• Reinheit: Affinity Purification
• Formulierung: Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:1000<br />ICC/IF: 1:20-1:100
• Anwendungsbeschreibung: IgG