APC1 (phospho-S688) polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: APC1 (phospho-S688) polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS4375
• Hersteller Artikelnummer: BS4375
• Alternativnummer: BWT-BS4375-50UL,BWT-BS4375-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic phosphopeptide derived from human APC1 around the phosphorylation site of Serine 688
• Konjugation: Unconjugated
• Alternative Synonym: Anaphase-promoting complex subunit 1, APC1, Cyclosome subunit 1, Mitotic checkpoint regulator, Testis-specific gene 24 protein, ANAPC1, TSG24

Produktbeschreibung

APC1 is 1 of at least 11 subunits of the anaphase promoting complex (APC), which functions at the metaphase to anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.

Produkteigenschaften

• Molekulargewicht: ~ 216 kDa
• UniProt: Q9H1A4
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500~1:1000
• Anwendungsbeschreibung: p-APC1 (S688) pAb detects endogenous levels of APC1 protein only when phosphorylated at Ser688.