Proteasome subunit alpha type 6 Recombinant Rabbit mAb, Unconjugated
Artikelnummer:
BWT-BS45256
Hersteller Artikelnummer:
BS45256
Alternativnummer:
BWT-BS45256-50UL,BWT-BS45256-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FC, ICC, WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
A synthetic peptide of human Proteasome subunit alpha type 6
Konjugation:
Unconjugated
Alternative Synonym:
IOTA, p27K, PROS27
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]
Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
