Dynein Light Chain Tctex Type 1 Recombinant Rabbit mAb, Unconjugated
Artikelnummer:
BWT-BS46370
Hersteller Artikelnummer:
BS46370
Alternativnummer:
BWT-BS46370-50UL,BWT-BS46370-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FC, ICC, IHC, IP, WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Recombinant protein of human TCTEX-1
Konjugation:
Unconjugated
Alternative Synonym:
CW-1, TCTEL1, tctex-1
This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
